【 文献重点摘要 】

The development of fractional photothermolysis has revolutionized the treatment of skin scarring, rejuvenation, and tightening. By creating targeted microthermal zones and leaving surrounding tissue intact, this concept has provided the field with efficacious results, with less downtime and a better safety profile. This has started to change the paradigm of what is considered first-line treatment for scarring and rejuvenation. While originally applied to nonablative lasers, fractionation has now been employed in ablative, quality-switched, picosecond, and novel hybrid fractional lasers. Furthermore, other energy-based technologies, such as radiofrequency, have adopted the concept of fractionation in an attempt to optimize the balance of efficacy, downtime, and side effects. Herein, we describe how the ever-expanding repertoire of fractional devices is applied to the treatment of scarring, skin rejuvenation, and tightening. In addition, newer applications, such as transdermal drug delivery, are being developed by using fractional devices. Growing experience with these devices has broadened their relevance to more skin types and body sites than ever. Ultimately, the knowledge of appropriate treatment parameters is paramount and allows for the safe and effective treatment of a variety of patients with numerous devices.

分步光热分解技术的发展使皮肤瘢痕、年轻化和紧致的治疗发生了革命性的变化。通过创建有针对性的低温区域并保持周围组织完好无损，这一概念为该领域提供了有效的结果，停机时间更短，安全性更好。这已经开始改变被认为是疤痕和年轻化的一线治疗的范式。虽然最初应用于非烧蚀激光器，但现在已用于烧蚀的、质量开关的、皮秒的和新颖的混合分数激光器。此外，其他以能量为基础的技术，如射频，也采用了分级的概念，试图优化功效、停机时间和副作用之间的平衡。在这里，我们描述了不断扩大的分部设备是如何应用于治疗瘢痕、皮肤年轻化和收紧的。此外，更新的应用，如经皮给药，正在通过使用分离设备来开发。越来越多的人对这些设备的体验使它们与更多的皮肤类型和身体部位的相关性比以往任何时候都要广泛。归根结底，了解适当的治疗参数是至关重要的，并允许使用多种设备对各种患者进行安全和有效的治疗。