Pattern analysis of laser-tattoo interactions for picosecond- and nanosecond-domain 1,064-nm
【 文献重点摘要 】
During laser treatment for tattoo removal, pigment chromophores absorb laser energy, resulting in fragmentation of the ink particles via selective photothermolysis. The present study aimed to outline macroscopic laser-tattoo interactions in tissue-mimicking (TM) phantoms treated with picosecond- and nanosecond-domain lasers. Additionally, high-speed cinematographs were captured to visualize time-dependent tattoo-tissue interactions, from laser irradiation to the formation of photothermal and photoacoustic injury zones (PIZs). In all experimental settings using the nanosecond or picosecond laser, tattoo pigments fragmented into coarse particles after a single laser pulse, and further disintegrated into smaller particles that dispersed toward the boundaries of PIZs after repetitive delivery of laser energy. Particles fractured by picosecond treatment were more evenly dispersed throughout PIZs than those fractured by nanosecond treatment. Additionally, picosecond-then-picosecond laser treatment (5-pass-picosecond treatment + 5-pass-picosecond treatment) induced greater disintegration of tattoo particles within PIZs than picosecond-then-nanosecond laser treatment (5-pass-picosecond treatment + 5-pass-nanosecond treatment). High-speed cinematography recorded the formation of PIZs after repeated reflection and propagation of acoustic waves over hundreds of microseconds to a few milliseconds. The present data may be of use in predicting three-dimensional laser-tattoo interactions and associated reactions in surrounding tissue.
在去除纹身的激光治疗过程中,颜料生色团吸收激光能量,通过选择性光热分解导致油墨颗粒碎裂。本研究旨在概述皮秒域和纳秒域激光处理的组织模拟(TM)模体中的宏观激光-纹身相互作用。此外,从激光照射到光热和光声损伤区(PIZ)的形成,捕捉高速电影以可视化纹身与组织之间的时间依赖的相互作用。在使用纳秒或皮秒激光的所有实验设置中,纹身颜料在单个激光脉冲后碎裂成粗颗粒,并在重复输送激光能量后进一步解体成更小的颗粒,向PIZ的边界扩散。皮秒处理的颗粒比纳秒处理的颗粒更均匀地分散在PIZ中。此外,皮秒和皮秒激光处理(5次皮秒处理+5次皮秒处理)比皮秒和纳秒激光处理(5次皮秒处理+5次纳秒处理)更能引起PIZ内纹身颗粒的解体。高速摄影记录了声波在数百微秒到几毫秒的重复反射和传播后形成的压电陶瓷带。目前的数据可能用于预测三维激光纹身相互作用和周围组织的相关反应。