【 文献重点摘要 】

Introduction

There is a paucity of studies on the use of chemical peels for acne scars among the Asian population. A trichloroacetic acid (TCA) and Jessner’s combination chemical peel, originally described by Monheit, is said to be better than a TCA peel alone.

Aims

The aim of the study was to compare the efficacy of 20% TCA and Jessner’s solution versus 20% TCA alone for the treatment of acne scars.

Materials and Methods

The patients were divided into two groups of 25 patients each. Chemical peeling was done in both the groups. In Group I, chemical peeling with Jessner’s peel followed by 20% TCA was done and in Group II patients chemical peeling with 20% TCA peel alone was done.

Results

In Group I (Jessner’s peel and 20% TCA), mild improvement of acne scars was seen in 8% cases, moderate improvement in 32% cases and marked improvement of acne scars was seen in 60% patients. In Group II (20% TCA), mild improvement of acne scars was seen in 32% cases, moderate improvement in 40% cases and marked improvement of acne scars was seen in 28% patients. But, the difference in improvement of acne scars was not statistically significant in both the groups (P value > 0.05).

KEYWORDS

Acne scars, chemical peels, hyperpigmentation, Jessner’s solution, trichloroacetic acid

导言

在亚洲人群中，关于使用化学去死皮治疗痤疮疤痕的研究很少。三氯乙酸(TCA)和杰斯纳化学去皮(最初由Monheit描述)的组合据说比单独使用TCA去皮要好。

目标

这项研究的目的是比较20%TCA和Jessner‘s溶液与单独使用20%TCA治疗痤疮瘢痕的疗效。

材料与方法

将患者分为两组，每组25例。两组均行化学剥脱术。Ⅰ组先用Jessner皮化学剥离，再用20%三氯乙酸(TCA)；Ⅱ组仅用20%三氯乙酸(TCA)进行化学剥离。

结果

Ⅰ组(Jessner‘s Peel和20%TCA)痤疮瘢痕轻度改善率为8%，中度改善率为32%，明显改善率为60%。Ⅱ组(20%TCA)痤疮瘢痕轻度改善率为32%，中度改善率为40%，明显改善率为28%。但两组痤疮瘢痕改善情况差异无统计学意义(P>0.05)。

关键词

痤疮疤痕，化学性脱皮，色素沉着，杰斯纳溶液，三氯乙酸