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Periorbital Hyperpigmentation: A Comprehensive Review
Rashmi Sarkar, MD
简介
【 文献重点摘要 】
Periorbital hyperpigmentation is a commonly encountered condition. There is very little scientific data available on the clinical profile and pathogenesis of periorbital hyperpigmentation. Periorbital hyperpigmentation is caused by various exogenous and endogenous factors. The causative factors include genetic or heredity, excessive pigmentation, postinflammatory hyperpigmentation secondary to atopic and allergic contact dermatitis, periorbital edema, excessive vascularity, shadowing due to skin laxity and tear trough associated with aging. There are a number of treatment options available for periorbital hyperpigmentation. Among the available alternatives to treat dark circles are topical depigmenting agents, such as hydroquinone, kojic acid, azelaic acid, and topical retinoic acid, and physical therapies, such as chemical peels, surgical corrections, and laser therapy, most of which are tried scientifically for melasma, another common condition of hyperpigmentation that occurs on the face. The aim of treatment should be to identify and treat the primary cause of hyperpigmentation as well as its contributing factors.
眼眶周围色素沉着是一种常见的情况。关于眶周色素沉着的临床特征和发病机制的科学数据很少。眶周色素沉着是由多种外源性和内源性因素引起的。其病因包括遗传或遗传、色素沉着过度、特应性和变态反应性接触性皮炎继发的炎症后色素沉着、眶周水肿、血管过多、皮肤松弛所致阴影和与衰老有关的泪沟等。眼眶周围色素沉着有多种治疗方法可供选择。治疗黑眼圈的有效选择包括局部脱色剂，如氢醌、曲酸、杜鹃酸和局部维甲酸，以及物理疗法，如化学换肤、手术矫正和激光疗法，其中大多数都是科学地尝试用于治疗黄褐斑，这是面部另一种常见的色素沉着情况。治疗的目的应该是确定和治疗色素沉着的主要原因及其影响因素。
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