软组织增大术与聚左旋乳酸的作用
Soft-Tissue Augmentation and the Role of PLLA
【 文献重点摘要 】
Background: Facial rejuvenation has traditionally centered on the correction of ptosis, lines, and wrinkles, typically achieved by surgical tightening of the skin or by injecting soft-tissue fillers. In recent years, volumetric augmentation and recontouring have been recognized as fundamentally important aspects of facial rejuvenation.
Methods: An overview of volume restoration and recontouring is presented. A literature search was also conducted to identify the injectable products representing potential treatment options for facial recontouring. The author also presents the results of his extensive experience with poly-L-lactic acid in the treatment of thousands of cosmetic patients in Europe, with special emphasis on the efficacy and tolerability of this product.
Results: Several injectable treatment options can be used to recontour and restore volume, to the face and beyond. All of these products, except calcium hydroxylapatite and poly-L-lactic acid, are nonresorbable, offering permanent volume augmentation, but with the increased risk of severe foreign-body reactions. Poly-L-lactic acid provides semipermanent results and has been documented to offer volume augmentation with a favorable safety profile. Achieving good efficacy and safety is dependent on the appropriate reconstitution of the product and adhering to the correct injection technique.
Conclusions: Injectable products offer a flexible means of recontouring the face and localized regions beyond the face. The potential of some of these products is supported by a wealth of published results and clinical experience, helping the physician to identify the most appropriate treatment for their patient.
背景:面部年轻化传统上集中在矫正上睑下垂、皱纹和皱纹,通常通过手术收紧皮肤或注射软组织填充物来实现。近年来,体积增大和轮廓重塑已被认为是面部年轻化的重要方面。
方法:对容积恢复和等值线重建法进行综述。还进行了一项文献搜索,以确定代表面部重塑的潜在治疗选择的可注射产品。作者还介绍了他在欧洲用聚左旋乳酸治疗数以千计的美容患者的广泛经验的结果,特别强调了该产品的有效性和耐受性。
结果:几种注射治疗方案可以用来重塑轮廓并恢复面部和更远的体积。除了羟基磷灰石和聚左旋乳酸之外,所有这些产品都是不可吸收的,提供永久性的容积增加,但增加了严重异物反应的风险。聚左旋乳酸提供了半永久性的结果,并已被证明提供了良好的安全概况的容积增加。要获得良好的疗效和安全性,取决于产品的适当重组和坚持正确的注射技术。
结论:注射产品提供了一种灵活的方法来重塑面部轮廓和面部以外的局部区域。其中一些产品的潜力得到了大量发表的结果和临床经验的支持,帮助医生确定对患者最合适的治疗方法。
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