【 文献重点摘要 】
 

Background

Injection techniques are growing, thanks to safer and more suitable filling agents. Hyaluronic acid (HA), a biodegradable product, has become the “gold standard” for fillers. With its wide range, it not only improves wrinkles but also restores volume.

Methods

Since 1996, many patients have been injected for wrinkles, fine lines, and nasolabial folds. For 3 years, more viscous HAs have been launched, allowing us to restore volumes. Some new procedures are described. These can correct anomalies of the chin and of the nose, and allow a betterment of the periocular area by correcting hollow and falling eyebrows.

Results

The use of different HAs for each area and indication is suitable and offers real possibilities to rejuvenate the skin without downtime. Longevity of the correction depends on treated areas, HA used, and on the individual.

Conclusion

HAs are safe and suitable for wrinkles and volume restoration, but besides their mechanical properties, they have numerous physiological functions. With the analysis of literature about the action mechanism of HA and its receptors, it is evident that HA also has a stimulating action on different physiological process.

Keywords

hyaluronic acid, hyaluronan interactions, filler, rejuvenation, volume restoration

背景

由于更安全和更合适的填充剂，注射技术正在发展。透明质酸(HA)是一种可生物降解的产品，已成为填充剂的“黄金标准”。它的使用范围很广，不仅能改善皱纹，还能恢复体量。

方法

自1996年以来，为许多患者注射治疗皱纹、细纹和鼻唇沟。三年来，已经推出了更多粘性产品，使我们能够恢复产量。介绍了一些新的方法。它们可以矫正下巴和鼻子的异常，并通过矫正凹陷和下垂的眉毛来改善眼周区域。

结果

针对不同部位、不同适应症使用不同的HAs是合适的，并提供了在不停机的情况下恢复皮肤活力的真正可能性。矫正的持续时间取决于治疗区域、使用的HA和个体。

结论

HAs除具有机械性能外，还具有多种生理功能，安全适用于皱纹和容积修复。通过对HA及其受体作用机制的文献分析，可以看出HA对不同的生理过程也有刺激作用。

关键词

透明质酸、透明质酸相互作用、填充剂、年轻化、容量恢复