【 文献重点摘要 】

Acquired bilateral nevus of Ota-like macules (ABNOM) is a common dermal lesion of melanotic hyperpigmentation in Asians. To treat ABNOM, various nanosecond-domain lasers, including Q-switched 694nm ruby, 1,064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG), and 755-nm alexandrite lasers, have been used. In this report, we treated a patient with ABNOM using 1,064-nm nanosecond-domain and picosecond-domain Nd:YAG lasers. At 3 months after one session of 1,064-nm nanosecond-domain Nd:YAG laser treatment, ABNOM lesions were partially improved. Then, an additional session of 1,064-nm picosecond-domain Nd:YAG laser treatment was delivered to ABNOM lesions. The patient presented nearly complete improvement thereof with no remarkable side effects or recurrence over the duration of 18 months. Picosecond-domain lasers were deemed to generate faster photothermal reactions, more extensive photoacoustic effects, and less injury to adjacent structures than nanosecond-domain lasers. We suggest that 1,064-nm picosecond-domain Nd:YAG laser can be effectively and safely used for treating pigmented lesions in the dermis, particularly ABNOM, in Asian patients.

Keywords

Acquired bilateral nevus of Ota-like macules; Picosecond; Nanosecond; Neodymium:yttrium-aluminum-garnet laser

获得性双侧太田样斑痣(ABNOM)是亚洲人常见的黑色素沉着皮损。为了治疗ABNOM，已经使用了各种纳秒域激光器，包括Q开关694 nm红宝石，1064 nm钕：钇铝石榴石(Nd：YAG)，以及755 nm紫翠宝石激光器。在这篇报道中，我们使用1064 nm的纳秒域和皮秒域的Nd：YAG激光器治疗了一例ABNOM患者。在1,064 nm纳秒域Nd：YAG激光治疗3个月后，ABNOM皮损部分改善。然后，对ABNOM皮秒区域的1064 nm Nd：YAG激光进行额外的治疗。患者在18个月的时间里几乎完全好转，没有明显的副作用或复发。皮秒域激光被认为比纳秒域激光产生更快的光热反应，更广泛的光声效应，并且对邻近结构的伤害更小。我们认为1064 nm皮秒域Nd：YAG激光可以安全有效地用于治疗亚洲患者真皮色素性病变，尤其是ABNOM。

关键词

获得性双侧太田样斑痣；皮秒；纳秒；钕：钇铝石榴石激光