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【肉毒素文献】A型肉毒毒素治疗脸红
Botulinum Toxin A in Treatment of Facial Flushing
简介
【 文献重点摘要 】
Flushing is a condition with episodic attacks of redness of the skin with a sensation of warmth or burning, this disease causes emotional and functional problems in patients. There is various treatments for this condition; one of them is the use of botulinum toxin A (BTA). In this prospective pilot study we studied the effect of Botulinum toxin A (BTA) effect on DLQI of patients with facial flushing, we compared the DLQI before and after treatment. The number of 24 women with facial flushing admitted to the department of dermatology of Hamadan Farshchian Hospital, with the age range of 18 to 60 was enrolled in the study. Patients completed Dermatology Quality of life Index questionnaire before and one month after treatment. In our study 1 unit of BTA was injected intracutaneously per square cm in both sides of cheeks, to a total dose of 30 units per session. All of 24 patients completed the study. The mean age was 37.79±13.13. In all patients, DLQI decreased, and in two months follow up, the mean of DLQI improved from 8.08±1.17 to 4.5±1.21 (P.value<0.005). Based on this study BTA is an effective and safe treatment for facial flushing.
Keywords: Flushing; Botulinum toxin A; Injection
潮红是一种间歇性的皮肤发红，有暖感或灼热感，这种疾病会导致患者的情绪和功能问题。这种情况有多种治疗方法，其中之一是使用A型肉毒毒素(BTA)。在这项前瞻性先导研究中，我们研究了A型肉毒毒素(BTA)对面红患者DLQI的影响，并对治疗前后的DLQI进行了比较。哈马丹·法尔什钦医院皮肤科收治24例面红的女性，年龄在18岁到60岁之间。患者在治疗前和治疗后1个月完成皮肤科生活质量指数问卷调查。在我们的研究中，在面颊两侧每平方厘米皮内注射1个单位的BTA，总剂量为30个单位/次。24名患者全部完成研究。平均年龄37.79±13.13岁。所有患者的生活质量指数均有不同程度的下降，随访2个月后，生活质量指数由术前的8.08±1.17提高到4.5±1.21(P.value<0.005)。基于这项研究，BTA是治疗脸红的一种有效而安全的治疗方法。
关键词：潮红；A型肉毒毒素；注射
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